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Target
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Ligand
BDBM50004699
Substrate
n/a
Meas. Tech.
ChEMBL_162010 (CHEMBL764181)
Kd
1.1±n/a nM
Citation
 Ishchenko, AV; Shakhnovich, EI SMall Molecule Growth 2001 (SMoG2001): an improved knowledge-based scoring function for protein-ligand interactions. J Med Chem 45:2770-80 (2002) [PubMed]  Article 
Target
Name:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Synonyms:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | 2A5A_HUMAN | PPP2R5A | Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform
Type:
PROTEIN
Mol. Mass.:
56194.06
Organism:
Human
Description:
ChEMBL_161424
Residue:
486
Sequence:
MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSILSNTSAE
  
Inhibitor
Name:
BDBM50004699
Synonyms:
CHEMBL96862 | CHEBI:45262 | US11185100, TABLE 9.3
Type:
Small organic molecule
Emp. Form.:
C10H13N4O7P
Mol. Mass.:
332.05
SMILES:
c1c2c(ncn1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O
Structure:
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