Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM50066960
Substrate
n/a
Meas. Tech.
ChEMBL_105272 (CHEMBL858415)
Ki
1.7±n/a nM
Citation
 Rivara, S; Mor, M; Silva, C; Zuliani, V; Vacondio, F; Spadoni, G; Bedini, A; Tarzia, G; Lucini, V; Pannacci, M; Fraschini, F; Plazzi, PV Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation. J Med Chem 46:1429-39 (2003) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
Mel-1B-R | Mel1b melatonin receptor | Melatonin receptor | Melatonin receptor type 1B | Melatonin 1B | Melatonin receptor type 2 (MT2) | MTR1B_HUMAN | MTNR1B
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Human
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50066960
Synonyms:
N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-acetamide | N-(2-(5-methoxy-1-methyl-1H-indol-3-yl)ethyl)acetamide | CHEMBL33700
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
COc1ccc2n(C)cc(CCNC(C)=O)c2c1
Structure:
Search PDB for entries with ligand similarity: