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Target
Melatonin receptor type 1A
Ligand
BDBM9019
Substrate
n/a
Meas. Tech.
ChEMBL_105111 (CHEMBL715954)
Ki
0.165959±n/a nM
Citation
 Rivara, S; Mor, M; Silva, C; Zuliani, V; Vacondio, F; Spadoni, G; Bedini, A; Tarzia, G; Lucini, V; Pannacci, M; Fraschini, F; Plazzi, PV Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation. J Med Chem 46:1429-39 (2003) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A protein | Mel-1A-R | Melatonin receptor type 1A | Mel1a melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin 1A | MTR1A_HUMAN | MTNR1A | Melatonin receptor
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Human
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM9019
Synonyms:
CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide | Melatonin
Type:
Small organic molecule
Emp. Form.:
C13H16N2O2
Mol. Mass.:
232.12
SMILES:
CC(=O)NCCc1c[nH]c2c1cc(cc2)OC
Structure:
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