Reaction Details Report a problem with these data
Target
Plasminogen
Ligand
BDBM50478442
Substrate
n/a
Meas. Tech.
ChEMBL_550109 (CHEMBL1004237)
IC50
99800±n/a nM
Citation
 Kodani, S; Ishida, K; Murakami, M Aeruginosin 103-A, a thrombin inhibitor from the cyanobacterium Microcystis viridis. J Nat Prod 61:1046-8 (1998) [PubMed]  Article 
Target
Name:
Plasminogen
Synonyms:
Plasmin heavy chain A | Plasmin heavy chain A, short form | Angiostatin | Plasmin light chain B | Plasmin | Activation peptide | PLMN_HUMAN | PLG
Type:
Enzyme
Mol. Mass.:
90579.18
Organism:
Human
Description:
n/a
Residue:
810
Sequence:
MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
  
Inhibitor
Name:
BDBM50478442
Synonyms:
Aeruginosin 103-A | CHEMBL503490
Type:
Small organic molecule
Emp. Form.:
C35H48N6O8
Mol. Mass.:
680.8
SMILES:
CCO[C@@H]1[C@H](CCCN1C(N)=N)NC(=O)C1CC2CCC(O)CC2N1C(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](O)Cc1ccc(O)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: