Reaction Details Report a problem with these data
Target
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Ligand
BDBM50484528
Substrate
n/a
Meas. Tech.
ChEMBL_791582 (CHEMBL1930719)
IC50
3160±n/a nM
Citation
 Shi, G; Shaw, G; Liang, YH; Subburaman, P; Li, Y; Wu, Y; Yan, H; Ji, X Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties. Bioorg Med Chem 20:47-57 (2012) [PubMed]  Article 
Target
Name:
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Synonyms:
JW0138 | PPPK | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase | HPPK | HPPK_ECOLI | folK
Type:
PROTEIN
Mol. Mass.:
18075.55
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_108237
Residue:
159
Sequence:
MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTPPLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLFGNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHTRAFDKLNKW
  
Inhibitor
Name:
BDBM50484528
Synonyms:
CHEMBL1928285
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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