Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 6
Ligand
BDBM31915
Substrate
n/a
Meas. Tech.
ChEMBL_838470 (CHEMBL2076041)
IC50
60000±n/a nM
Citation
 Cihlar, T; Ho, ES Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1. Anal Biochem 283:49-55 (2000) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
hPAHT | PAH transporter | Renal organic anion transporter 1 | hOAT1 | hROAT1 | Organic anion transporter 1 | S22A6_HUMAN | SLC22A6 | OAT1 | PAHT
Type:
PROTEIN
Mol. Mass.:
61831.78
Organism:
Human
Description:
ChEMBL_1487359
Residue:
563
Sequence:
MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQTRQQQEHQKYMVPLQASAQEKNGL
  
Inhibitor
Name:
BDBM31915
Synonyms:
HPMPC | Vistide | CDV | Cidofovir | US10071110, Compound Cidofovir
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: