Reaction Details
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Retinoic acid receptor beta
Ligand
BDBM31883
Substrate
n/a
Meas. Tech.
ChEMBL_195814 (CHEMBL799663)
Kd
12±n/a nM
Citation
Johnson, AT; Klein, ES; Gillett, SJ; Wang, L; Song, TK; Pino, ME; Chandraratna, RA Synthesis and characterization of a highly potent and effective antagonist of retinoic acid receptors. J Med Chem 38:4764-7 (1996) [PubMed] Article More Info.:
Target
Name:
Retinoic acid receptor beta
Synonyms:
RAR-beta | RAR-epsilon | HBV-activated protein | Nuclear receptor subfamily 1 group B member 2 | Retinoic acid receptor beta | RARB_HUMAN | RARB | HAP | NR1B2 | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
50498.70
Organism:
Human
Description:
ChEMBL_1458015
Residue:
455
Sequence:
MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPATIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
Inhibitor
Name:
BDBM31883
Synonyms:
ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_444795 | [3H]RA | AT-RA | TRETINOIN | [3H]tretinoin | all-trans retinoic acid | CHEMBL38 | Vitamin A acid | MLS000028588 | [3H]Vitamin A acid | 9-cis-retinoic acid (9cRA) | [3H]Retinoic acid | Atralin
Type:
radiolabeled ligand
Emp. Form.:
C20H28O2
Mol. Mass.:
300.21
SMILES:
CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C
Structure:
