Reaction Details Report a problem with these data
Target
Trophozoite cysteine proteinase
Ligand
BDBM50452355
Substrate
n/a
Meas. Tech.
ChEMBL_903031 (CHEMBL3063284)
IC50
3200±n/a nM
Citation
  TBA Med Chem Res 21:3835-3847 (2012)    Article 
Target
Name:
Trophozoite cysteine proteinase
Synonyms:
3.4.22.- | TCP | Trophozoite cysteine proteinase | CYSP_PLAFA
Type:
PROTEIN
Mol. Mass.:
66893.11
Organism:
malaria parasite P. falciparum
Description:
ChEMBL_106615
Residue:
569
Sequence:
MVAIKEMKELAFARPSLVETLNKKKKFLKKKEKRTFVLSIYAFITFIIFCIGILYFTNKSSAHNNNNNKNEHSLKKEEIELLRVLLEKYKKQKDGILNESSNEEDEEKYTLNSETYNNKNNVSNIKNDSIKSKKEEYINLERILLEKYKKFINENNEENRKELSNILHKLLEINKLILREEKDDKKVYLINDNYDEKGALEIGMNEEMKYKKEDPINNIKYASKFFKFMKEHNKVYKNIDEQMRKFEIFKINYISIKNHNKLNKNAMYKKKVNQFSDYSEEELKEYFKTLLHVPNHMIEKYSKPFENHLKDNILISEFYTNGKRNEKDIFSKVPEILDYREKGIVHEPKDQGLCGSCWAFASVGNIESVFAKKNKNILSFSEQEVVDCSKDNFGCDGGHPFYSFLYVLQNELCLGDEYKYKAKDDMFCLNYRCKRKVSLSSIGAVKENQLILALNEVGPLSVNVGVNNDFVAYSEGVYNGTCSEELNHSVLLVGYGQVEKTKLNYNNKIQTYNTKENSNQPDDNIIYYWIIKNSWSKKWGENGFMRLSRNKNGDNVFCGIGEEVFYPIL
  
Inhibitor
Name:
BDBM50452355
Synonyms:
CHEMBL2237710
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: