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Target
Retinoic acid receptor RXR-gamma
Ligand
BDBM50032662
Substrate
n/a
Meas. Tech.
ChEMBL_197226 (CHEMBL798202)
Kd
283±n/a nM
Citation
 Boehm, MF; Zhang, L; Zhi, L; McClurg, MR; Berger, E; Wagoner, M; Mais, DE; Suto, CM; Davies, JA; Heyman, RA Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem 38:3146-55 (1995) [PubMed]  Article 
Target
Name:
Retinoic acid receptor RXR-gamma
Synonyms:
Nr2b3 | RXRG_MOUSE | Retinoid X receptor gamma | Rxrg
Type:
PROTEIN
Mol. Mass.:
50900.28
Organism:
Mus musculus
Description:
ChEMBL_196589
Residue:
463
Sequence:
MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSSHEDMPVERILEAELAVEPKTESYGDMNVENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDSFLMEMLETPLQIT
  
Inhibitor
Name:
BDBM50032662
Synonyms:
4-[1-(1,1,2,3,3,6-Hexamethyl-indan-5-yl)-vinyl]-benzoic acid | CHEMBL106837
Type:
Small organic molecule
Emp. Form.:
C24H28O2
Mol. Mass.:
348.4779
SMILES:
CC1C(C)(C)c2cc(C)c(cc2C1(C)C)C(=C)c1ccc(cc1)C(O)=O
Structure:
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