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Target
Carnitine O-palmitoyltransferase 1, liver isoform
Ligand
BDBM50033117
Substrate
n/a
Meas. Tech.
ChEMBL_46332 (CHEMBL662623)
Ki
3600±n/a nM
Citation
 Anderson, RC; Balestra, M; Bell, PA; Deems, RO; Fillers, WS; Foley, JE; Fraser, JD; Mann, WR; Rudin, M; Villhauer, EB Antidiabetic agents: a new class of reversible carnitine palmitoyltransferase I inhibitors. J Med Chem 38:3448-50 (1995) [PubMed]  Article 
Target
Name:
Carnitine O-palmitoyltransferase 1, liver isoform
Synonyms:
CPT I | CPT1-L | CPTI-L | Carnitine O-palmitoyltransferase I, liver isoform | CPT1A_RAT | Cpt1a | Cpt-1 | Cpt1 | Carnitine palmitoyltransferase 1A
Type:
PROTEIN
Mol. Mass.:
88147.11
Organism:
Rat
Description:
ChEMBL_887445
Residue:
773
Sequence:
MAEAHQAVAFQFTVTPDGIDLRLSHEALKQICLSGLHSWKKKFIRFKNGIITGVFPANPSSWLIVVVGVISSMHAKVDPSLGMIAKISRTLDTTGRMSSQTKNIVSGVLFGTGLWVAVIMTMRYSLKVLLSYHGWMFAEHGKMSRSTKIWMAMVKVLSGRKPMLYSFQTSLPRLPVPAVKDTVSRYLESVRPLMKEEDFQRMTALAQDFAVNLGPKLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMEMLYITPTHIQAARAGNTIHAILLYRRTLDREELKPIRLLGSTIPLCSAQWERLFNTSRIPGEETDTIQHIKDSRHIVVYHRGRYFKVWLYHDGRLLRPRELEQQMQQILDDPSEPQPGEAKLAALTAADRVPWAKCRQTYFARGKNKQSLDAVEKAAFFVTLDESEQGYREEDPEASIDSYAKSLLHGRCFDRWFDKSITFVVFKNSKIGINAEHSWADAPVVGHLWEYVMATDVFQLGYSEDGHCKGDTNPNIPKPTRLQWDIPGECQEVIDASLSSASLLANDVDLHSFPFDSFGKGLIKKCRTSPDAFIQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTMESCNFVQAMMDPKSTAEQRLKLFKIACEKHQHLYRLAMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELFDFEKNPDYVSCGGGFGPVADDGYGVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQAMMDIITLFGLTINSKK
  
Inhibitor
Name:
BDBM50033117
Synonyms:
[3-Carboxy-2-(hydroxy-tetradecyloxy-phosphoryloxy)-propyl]-trimethyl-ammonium | CHEMBL114113
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCCCCCCCCCCCCCOP([O-])(=O)O[C@H](CC(O)=O)C[N+](C)(C)C
Structure:
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