Reaction Details Report a problem with these data
Target
Acyl-protein thioesterase 1
Ligand
BDBM207991
Substrate
n/a
Meas. Tech.
ChEMBL_1300899 (CHEMBL3135186)
Ki
300±n/a nM
Citation
 Davda, D; Martin, BR Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation. Medchemcomm 5:268-276 (2014) [PubMed]  Article 
Target
Name:
Acyl-protein thioesterase 1
Synonyms:
APT-1 | LPL-I | LysoPLA I | hAPT1 | Lysophospholipase I | Acyl-protein thioesterase 1 (APT1 WT) | Lysophospholipase 1 | LYPA1_HUMAN | LYPLA1 | APT1 | LPL1
Type:
Protein
Mol. Mass.:
24670.33
Organism:
Human
Description:
O75608
Residue:
230
Sequence:
MCGNNMSTPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRPVTLNMNVAMPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPLMFGSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPID
  
Inhibitor
Name:
BDBM207991
Synonyms:
ML348
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
c1cc(oc1)C(=O)N2CCN(CC2)CC(=O)Nc3cc(ccc3Cl)C(F)(F)F
Structure:
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