Reaction Details Report a problem with these data
Target
Retinoic acid receptor gamma
Ligand
BDBM50055112
Substrate
n/a
Meas. Tech.
ChEMBL_196328 (CHEMBL806271)
Kd
>10±n/a nM
Citation
 Johnson, AT; Klein, ES; Wang, L; Pino, ME; Chandraratna, RA Identification of retinoic acid receptor beta subtype specific agonists. J Med Chem 39:5027-30 (1997) [PubMed]  Article 
Target
Name:
Retinoic acid receptor gamma
Synonyms:
NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
50345.43
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458016
Residue:
454
Sequence:
MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
  
Inhibitor
Name:
BDBM50055112
Synonyms:
4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-naphthalene-2-carbonyl)-amino]-benzoic acid | CHEMBL344973
Type:
Small organic molecule
Emp. Form.:
C24H21NO3S
Mol. Mass.:
403.493
SMILES:
CC1(C)CC=C(c2cccs2)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O |t:4|
Structure:
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