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Target
Prostaglandin G/H synthase 2
Ligand
BDBM22360
Substrate
n/a
Meas. Tech.
ChEMBL_157996 (CHEMBL766669)
IC50
660000±n/a nM
Citation
 Hopper, AT; Witiak, DT; Ziemniak, J Design, synthesis, and biological evaluation of conformationally constrained aci-reductone mimics of arachidonic acid. J Med Chem 41:420-7 (1998) [PubMed]  Article 
Target
Name:
Prostaglandin G/H synthase 2
Synonyms:
Cyclooxygenase-1 (COX-1) | Cyclooxygenase-2 (COX-2) | PGH2_SHEEP | PTGS2 | COX2 | Prostaglandin G/H synthase (cyclooxygenase) | Prostaglandin G/H synthase (Cyclooxygenase-2)
Type:
Protein
Mol. Mass.:
68976.98
Organism:
Sheep
Description:
n/a
Residue:
603
Sequence:
MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL
  
Inhibitor
Name:
BDBM22360
Synonyms:
2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate | Polopirin | cid_2244 | Zorprin | Acetylsalicylic acid | acetylsalicylate | Endosprin | Aspirin
Type:
Anti-Inflammatory Agents, Non-Steroidal
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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