Reaction Details Report a problem with these data
Target
All-trans-retinol dehydrogenase [NAD(+)] ADH1B
Ligand
BDBM50064285
Substrate
n/a
Meas. Tech.
ChEMBL_31169 (CHEMBL641134)
Ki
250000±n/a nM
Citation
 Schindler, JF; Berst, KB; Plapp, BV Inhibition of human alcohol dehydrogenases by formamides. J Med Chem 41:1696-701 (1998) [PubMed]  Article 
Target
Name:
All-trans-retinol dehydrogenase [NAD(+)] ADH1B
Synonyms:
Alcohol dehydrogenase beta chain | ADH1B_HUMAN | ADH1B | ADH2 | Alcohol dehydrogenase
Type:
PROTEIN
Mol. Mass.:
39864.68
Organism:
Human
Description:
ChEMBL_31169
Residue:
375
Sequence:
MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLTF
  
Inhibitor
Name:
BDBM50064285
Synonyms:
N-Cyclohexyl-N-cyclopropyl-formamide | CHEMBL294911
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: