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Target
L-lactate dehydrogenase B chain
Ligand
BDBM50066977
Substrate
n/a
Meas. Tech.
ChEMBL_96432 (CHEMBL706379)
Ki
49000±n/a nM
Citation
 Deck, LM; Royer, RE; Chamblee, BB; Hernandez, VM; Malone, RR; Torres, JE; Hunsaker, LA; Piper, RC; Makler, MT; Vander Jagt, DL Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum. J Med Chem 41:3879-87 (1998) [PubMed]  Article 
Target
Name:
L-lactate dehydrogenase B chain
Synonyms:
LDH-H | L-lactate dehydrogenase B | LDH heart subunit | LDH-B | Renal carcinoma antigen NY-REN-46 | LDHB_HUMAN | LDHB | L-lactate dehydrogenase B chain | Lactate dehydrogenase B (LDHB)
Type:
Oxidoreductase; homotetramer
Mol. Mass.:
36635.55
Organism:
Human
Description:
n/a
Residue:
334
Sequence:
MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
  
Inhibitor
Name:
BDBM50066977
Synonyms:
2,3-Dihydroxy-6-methyl-4-propyl-naphthalene-1-carboxylic acid | CHEMBL127327
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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