Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50386790
Substrate
n/a
Meas. Tech.
ChEMBL_1883825 (CHEMBL4385324)
EC50
31±n/a nM
Citation
 Huang, H; Meegalla, SK; Lanter, JC; Winters, MP; Zhao, S; Littrell, J; Qi, J; Rady, B; Lee, PS; Liu, J; Martin, T; Lam, WW; Xu, F; Lim, HK; Wilde, T; Silva, J; Otieno, M; Pocai, A; Player, MR Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α-Fluorination. ACS Med Chem Lett 10:16-21 (2019) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
G-protein Coupled Receptor 40 | FFAR1_HUMAN | FFAR1 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Human
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50386790
Synonyms:
CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US11905230, Example TAK-875
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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