Reaction Details Report a problem with these data
Target
Cell division cycle protein 20 homolog
Ligand
BDBM50527908
Substrate
n/a
Meas. Tech.
ChEMBL_1903906 (CHEMBL4406128)
Kd
161000±n/a nM
Citation
 Huang, P; Le, X; Huang, F; Yang, J; Yang, H; Ma, J; Hu, G; Li, Q; Chen, Z Discovery of a Dual Tubulin Polymerization and Cell Division Cycle 20 Homologue Inhibitor via Structural Modification on Apcin. J Med Chem 63:4685-4700 (2020) [PubMed]  Article 
Target
Name:
Cell division cycle protein 20 homolog
Synonyms:
Cell division cycle protein 20 homolog | p55CDC | CDC20_HUMAN | CDC20
Type:
PROTEIN
Mol. Mass.:
54744.11
Organism:
Human
Description:
ChEMBL_119033
Residue:
499
Sequence:
MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQGIR
  
Inhibitor
Name:
BDBM50527908
Synonyms:
CHEMBL4520724
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: