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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50361373
Substrate
n/a
Meas. Tech.
ChEMBL_1929832 (CHEMBL4433008)
IC50
600±n/a nM
Citation
 Lee, HW; Ryu, HW; Kang, MG; Park, D; Oh, SR; Kim, H Potent selective monoamine oxidase B inhibition by maackiain, a pterocarpan from the roots of Sophora flavescens. Bioorg Med Chem Lett 26:4714-4719 (2016) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
Amine oxidase [flavin-containing] B | Monoamine oxidase type B | MAO-B | AOFB_MOUSE | Maob | Monoamine oxidase | Monoamine Oxidase Type B (MAO-B)
Type:
PROTEIN
Mol. Mass.:
58568.67
Organism:
Mouse
Description:
ChEMBL_605809
Residue:
520
Sequence:
MSNKSDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDNNNLWRTMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTKSTKQIATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQTGENVIVKTLNHEIYEAKYVISAIPPALGMKIHYSPPLPMLRNQLISRVPLGSVIKCMVYYKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGTYAAIMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVGKIFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESLDVPARPITSTFLERHLPSVPGLLKLFGLTTILSATALGFLAHKRGLFVHF
  
Inhibitor
Name:
BDBM50361373
Synonyms:
AURAPTENE
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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