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Target
Vitamin D3 receptor A
Ligand
BDBM50409927
Substrate
n/a
Meas. Tech.
ChEMBL_1988731 (CHEMBL4622278)
Kd
>30000±n/a nM
Citation
 Belorusova, AY; Chalhoub, S; Rovito, D; Rochel, N Structural Analysis of VDR Complex with ZK168281 Antagonist. J Med Chem 63:9457-9463 (2020) [PubMed]  Article 
Target
Name:
Vitamin D3 receptor A
Synonyms:
1,25-dihydroxyvitamin D3 receptor A | Nuclear receptor subfamily 1 group I member 1-A | VDR-A | Vitamin D3 receptor A | VDRA_DANRE | vdra | nr1i1a | vdr
Type:
PROTEIN
Mol. Mass.:
50869.54
Organism:
Zebrafish
Description:
ChEMBL_108257
Residue:
453
Sequence:
MLTENSAVNSGGKSKCEAGACESRVNGDATSVMDLMAVSTSATGQDEFDRNAPRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKASFTCPFNGNCTITKDNRRHCQACRLKRCIDIGMMKEFILTDEEVQRKKDLIMKRKEEEAAREARKPRLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVREGPVTRSASRAASLHSLSDASSDSFNHSPESVDTKLNFSNLLMMYQDSGSPDSSEEDQQSRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS
  
Inhibitor
Name:
BDBM50409927
Synonyms:
CHEMBL2112315
Type:
Small organic molecule
Emp. Form.:
C32H46O5
Mol. Mass.:
n/a
SMILES:
CCOC(=O)\C=C\C1(CC1)[C@H](O)\C=C\[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C
Structure:
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