Reaction Details Report a problem with these data
Target
Histone deacetylase 2b
Ligand
BDBM19149
Substrate
n/a
Meas. Tech.
ChEMBL_87880 (CHEMBL698799)
IC50
50±n/a nM
Citation
 Mai, A; Massa, S; Ragno, R; Esposito, M; Sbardella, G; Nocca, G; Scatena, R; Jesacher, F; Loidl, P; Brosch, G Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation. J Med Chem 45:1778-84 (2002) [PubMed]  Article 
Target
Name:
Histone deacetylase 2b
Synonyms:
Histone deacetylase HD2
Type:
PROTEIN
Mol. Mass.:
30785.07
Organism:
Maize
Description:
ChEMBL_87549
Residue:
286
Sequence:
MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVEKHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQNNEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEMSEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSEQSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
  
Inhibitor
Name:
BDBM19149
Synonyms:
Zolinza | suberoylanilide hydroxamic acid | CHEMBL98 | cid_5311 | N-hydroxy-N'-phenyloctanediamide | Vorinostat | SAHA | US9115116, SAHA | US9695181, Vorinostat | US9428447, SAHA | US9353061, SAHA | US10188756, Compound SAHA | US10011611, SAHA | US11207431, SAHA | US11505523, Compound SAHA | US20240327418, Example SAHA
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: