Reaction Details Report a problem with these data
Target
Ribosyldihydronicotinamide dehydrogenase [quinone]
Ligand
BDBM50066960
Substrate
n/a
Meas. Tech.
ChEMBL_104942 (CHEMBL713109)
Ki
2.8±n/a nM
Citation
 Leclerc, V; Yous, S; Delagrange, P; Boutin, JA; Renard, P; Lesieur, D Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3). J Med Chem 45:1853-9 (2002) [PubMed]  Article 
Target
Name:
Ribosyldihydronicotinamide dehydrogenase [quinone]
Synonyms:
QR2 | Quinone reductase 2 (NQO2) | Metallothionein-3 | NRH:quinone oxidoreductase 2 | Ribosyldihydronicotinamide dehydrogenase [quinone] | NRH dehydrogenase [quinone] 2 | Quinone reductase 2 | NQO2_HUMAN | NQO2 | NMOR2
Type:
Protein
Mol. Mass.:
25917.25
Organism:
Human
Description:
P16083
Residue:
231
Sequence:
MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
  
Inhibitor
Name:
BDBM50066960
Synonyms:
N-[2-(5-Methoxy-1-methyl-1H-indol-3-yl)-ethyl]-acetamide | N-(2-(5-methoxy-1-methyl-1H-indol-3-yl)ethyl)acetamide | CHEMBL33700
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
COc1ccc2n(C)cc(CCNC(C)=O)c2c1
Structure:
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