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Target
Retinoic acid receptor beta
Ligand
BDBM50120064
Substrate
n/a
Meas. Tech.
ChEMBL_39041 (CHEMBL652855)
Kd
1470±n/a nM
Citation
 Beard, RL; Duong, TT; Teng, M; Klein, ES; Standevan, AM; Chandraratna, RA Synthesis and biological activity of retinoic acid receptor-alpha specific amides. Bioorg Med Chem Lett 12:3145-8 (2002) [PubMed]  Article 
Target
Name:
Retinoic acid receptor beta
Synonyms:
HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
50498.70
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458015
Residue:
455
Sequence:
MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPATIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
  
Inhibitor
Name:
BDBM50120064
Synonyms:
2,6-Difluoro-4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-amino]-benzoic acid | CHEMBL106527
Type:
Small organic molecule
Emp. Form.:
C22H23F2NO3
Mol. Mass.:
387.4197
SMILES:
CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1cc(F)c(C(O)=O)c(F)c1
Structure:
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