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Target
Protein odd-skipped-related 1
Ligand
BDBM2579
Substrate
n/a
Meas. Tech.
ChEMBL_2065368 (CHEMBL4720621)
IC50
19.1±n/a nM
Citation
 Hou, W; Ren, Y; Zhang, Z; Sun, H; Ma, Y; Yan, B Novel quinazoline derivatives bearing various 6-benzamide moieties as highly selective and potent EGFR inhibitors. Bioorg Med Chem 26:1740-1750 (2018) [PubMed]  Article 
Target
Name:
Protein odd-skipped-related 1
Synonyms:
Protein odd-skipped-related 1 | OSR1_HUMAN | OSR1 | ODD
Type:
PROTEIN
Mol. Mass.:
29638.12
Organism:
Human
Description:
ChEMBL_119156
Residue:
266
Sequence:
MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGTVSSLVDARFQLPAFPWFPHVIQPKPEITAGGSVPALKTKPRFDFANLALAATQEDPAKLGRGEGPGSPAGGLGALLDVTKLSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC
  
Inhibitor
Name:
BDBM2579
Synonyms:
CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 | (2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one | Staurosporine | US9206188, Staurosporine | US9226923, Staurosporine | US20240002365, Compound staurosporine | US11958831, Example Staurosporine | US20240254124, Compound Staurosporine | US20240309004, Compound STAUROSPORINE
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: