Reaction Details Report a problem with these data
Target
Arginase-2, mitochondrial
Ligand
BDBM50561049
Substrate
n/a
Meas. Tech.
ChEMBL_2074199 (CHEMBL4729733)
IC50
100±n/a nM
Citation
 Borek, B; Gajda, T; Golebiowski, A; Blaszczyk, R Boronic acid-based arginase inhibitors in cancer immunotherapy. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Arginase-2, mitochondrial
Synonyms:
Arginase II | Kidney-type arginase | Non-hepatic arginase | Type II arginase | ARGI2_HUMAN | ARG2
Type:
PROTEIN
Mol. Mass.:
38576.93
Organism:
Human
Description:
ChEMBL_978892
Residue:
354
Sequence:
MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
  
Inhibitor
Name:
BDBM50561049
Synonyms:
CHEMBL4793482
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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