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Target
Interstitial collagenase
Ligand
BDBM50063917
Substrate
n/a
Meas. Tech.
ChEBML_106150
Ki
1.1±n/a nM
Citation
 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Structure--activity relationships of azasugar-based MMP/ADAM inhibitors. Bioorg Med Chem Lett 13:2737-40 (2003) [PubMed]  Article 
Target
Name:
Interstitial collagenase
Synonyms:
Fibroblast collagenase | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) | MMP1_HUMAN | MMP1 | CLG
Type:
Enzyme
Mol. Mass.:
54010.26
Organism:
Human
Description:
P03956
Residue:
469
Sequence:
MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
  
Inhibitor
Name:
BDBM50063917
Synonyms:
CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: