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Target
Retinoic acid receptor RXR-beta
Ligand
BDBM50141602
Substrate
n/a
Meas. Tech.
ChEBML_196588
Ki
>10000±n/a nM
Citation
 Michellys, PY; D'Arrigo, J; Grese, TA; Karanewsky, DS; Leibowitz, MD; Mais, DA; Mapes, CM; Reifel-Miller, A; Rungta, D; Boehm, MF Design, synthesis and structure-activity relationship of novel RXR-selective modulators. Bioorg Med Chem Lett 14:1593-8 (2004) [PubMed]  Article  BDB Entry
Target
Name:
Retinoic acid receptor RXR-beta
Synonyms:
Retinoid X receptor beta
Type:
PROTEIN
Mol. Mass.:
55877.78
Organism:
Mus musculus
Description:
ChEMBL_196588
Residue:
520
Sequence:
MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
  
Inhibitor
Name:
BDBM50141602
Synonyms:
(E)-3-{7-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]-benzofuran-2-yl}-but-2-enoic acid | CHEMBL290399
Type:
Small organic molecule
Emp. Form.:
C27H31FO4
Mol. Mass.:
438.531
SMILES:
CC(C)c1cc(C(C)C)c(OCCCF)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O
Structure:
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