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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50144842
Substrate
n/a
Meas. Tech.
ChEMBL_2263 (CHEMBL617050)
EC50
62±n/a nM
Citation
 Bentley, JM; Adams, DR; Bebbington, D; Benwell, KR; Bickerdike, MJ; Davidson, JE; Dawson, CE; Dourish, CT; Duncton, MA; Gaur, S; George, AR; Giles, PR; Hamlyn, RJ; Kennett, GA; Knight, AR; Malcolm, CS; Mansell, HL; Misra, A; Monck, NJ; Pratt, RM; Quirk, K; Roffey, JR; Vickers, SP; Cliffe, IA Indoline derivatives as 5-HT(2C) receptor agonists. Bioorg Med Chem Lett 14:2367-70 (2004) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
Serotonin receptor 2A | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Human
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM50144842
Synonyms:
(S)-1-Methyl-2-(2,3,7,8-tetrahydro-furo[2,3-g]indol-1-yl)-ethylamine | VER-5384 | CHEMBL77880
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
218.14
SMILES:
C[C@H](N)CN1CCc2ccc3OCCc3c12
Structure:
Search PDB for entries with ligand similarity: