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Target
Transcription factor 4
Ligand
BDBM50094484
Substrate
n/a
Meas. Tech.
ChEMBL_2192887 (CHEMBL5105247)
IC50
10000±n/a nM
Citation
 McCoy, MA; Spicer, D; Wells, N; Hoogewijs, K; Fiedler, M; Baud, MGJ Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale. J Med Chem 65:7246-7261 (2022) [PubMed] 
Target
Name:
Transcription factor 4
Synonyms:
Class B basic helix-loop-helix protein 19 | ITF-2 | Immunoglobulin transcription factor 2 | SEF-2 | SL3-3 enhancer factor 2 | TCF-4 | Transcription factor 4 | ITF2_HUMAN | TCF4 | BHLHB19 | ITF2 | SEF2
Type:
PROTEIN
Mol. Mass.:
71315.43
Organism:
Human
Description:
ChEMBL_117085
Residue:
667
Sequence:
MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM
  
Inhibitor
Name:
BDBM50094484
Synonyms:
CHEMBL2323033 | CHEBI:3556 | US9284299, CGP049090 | US9738628, Compound CGP049090
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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