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Target
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Ligand
BDBM76903
Substrate
n/a
Meas. Tech.
ChEMBL_2193440 (CHEMBL5105800)
IC50
5684±n/a nM
Citation
 Lee, B; Gyu Kim, D; Mi Kim, Y; Kim, S; Choi, I Discovery of benzodioxane analogues as lead candidates of AIMP2-DX2 inhibitors. Bioorg Med Chem Lett 73:0 (2022) [PubMed] 
Target
Name:
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Synonyms:
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 | JTV1 | Multisynthase complex auxiliary component p38 | Protein JTV-1 | AIMP2_HUMAN | AIMP2 | JTV1
Type:
PROTEIN
Mol. Mass.:
35355.45
Organism:
Human
Description:
ChEMBL_119035
Residue:
320
Sequence:
MPMYQVKPYHGGGAPLRVELPTCMYRLPNVHGRSYGPAPGAGHVQEESNLSLQALESRQDDILKRLYELKAAVDGLSKMIQTPDADLDVTNIIQADEPTTLTTNALDLNSVLGKDYGALKDIVINANPASPPLSLLVLHRLLCEHFRVLSTVHTHSSVKSVPENLLKCFGEQNKKQPRQDYQLGFTLIWKNVPKTQMKFSIQTMCPIEGEGNIARFLFSLFGQKHNAVNATLIDSWVDIAIFQLKEGSSKEKAAVFRSMNSALGKSPWLAGNELTVADVVLWSVLQQIGGCSVTVPANVQRWMRSCENLAPFNTALKLLK
  
Inhibitor
Name:
BDBM76903
Synonyms:
N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(6-methyl-1-benzofuran-3-yl)ethanamide | N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(6-methyl-3-benzofuranyl)acetamide | SMR000066659 | cid_2999286 | MLS000055798 | N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(6-methyl-1-benzofuran-3-yl)acetamide | N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(6-methylbenzofuran-3-yl)acetamide
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: