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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM21342
Substrate
n/a
Meas. Tech.
ChEMBL_2207712 (CHEMBL5120420)
EC50
5.4±n/a nM
Citation
 Poulie, CBM; Pottie, E; Simon, IA; Harpsøe, K; D'Andrea, L; Komarov, IV; Gloriam, DE; Jensen, AA; Stove, CP; Kristensen, JL Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT J Med Chem 65:12031-12043 (2022) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
Serotonin receptor 2A | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Human
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM21342
Synonyms:
(4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide | Lysergic Acid Diethylamide Tartrate | LSD | CHEMBL263881 | LSD,(+) | LSD,l- | Lysergic Acid Diethylamide | d-Isolysergic acid amide | LSD 25 | [3H]-LSD | US20240166618, Compound LSD | US20240368151, Compound LSD
Type:
radiolabeled ligand
Emp. Form.:
C20H25N3O
Mol. Mass.:
323.20
SMILES:
CCN(CC)C(=O)[C@H]1CN([C@@H]2Cc3c[nH]c4c3c(ccc4)C2=C1)C
Structure:
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