Reaction Details Report a problem with these data
Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50383373
Substrate
n/a
Meas. Tech.
ChEMBL_2212719 (CHEMBL5125668)
EC50
3400±n/a nM
Citation
 Nguyen, M; An, S; Nguyen, Y; Hyun, YE; Choi, H; Pham, L; Kim, JA; Noh, M; Kim, G; Jeong, LS Design, Synthesis, and Biological Activity of l-1'-Homologated Adenosine Derivatives. ACS Med Chem Lett 13:1131-1136 (2022) [PubMed] 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
Peroxisome proliferator-activated receptor delta | PPAR delta | NUCI | Nuclear hormone receptor 1 | NUC1 | Nuclear receptor subfamily 1 group C member 2 | Peroxisome proliferator-activated receptor beta | PPAR-beta | PPARD_HUMAN | PPARD | NR1C2 | PPARB | Peroxisome proliferator-activated receptor
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Human
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50383373
Synonyms:
GSK0660 | CHEMBL592652
Type:
Small organic molecule
Emp. Form.:
C19H18N2O5S2
Mol. Mass.:
n/a
SMILES:
COC(=O)c1sccc1S(=O)(=O)Nc1ccc(Nc2ccccc2)cc1OC
Structure:
Search PDB for entries with ligand similarity: