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Target
Angiotensin-converting enzyme 2
Ligand
BDBM50157304
Substrate
n/a
Meas. Tech.
ChEMBL_2215977 (CHEMBL5129109)
Kd
16980±n/a nM
Citation
 Xu, T; Meng, JR; Cheng, W; Liu, JZ; Chu, J; Zhang, Q; Ma, N; Bai, LP; Guo, Y Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors. Bioorg Med Chem 67:0 (2022) [PubMed] 
Target
Name:
Angiotensin-converting enzyme 2
Synonyms:
Angiotensin-converting enzyme-related carboxypeptidase | ACEH | ACE-related carboxypeptidase | Angiotensin-converting enzyme homolog | Metalloprotease MPROT15 | ACE2_HUMAN | ACE2
Type:
Enzyme
Mol. Mass.:
92448.86
Organism:
Human
Description:
n/a
Residue:
805
Sequence:
MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNPGFQNTDDVQTSF
  
Inhibitor
Name:
BDBM50157304
Synonyms:
3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid_72303 | 3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 5,3''-Diallyl-biphenyl-2,4''-diol | Honokiol, HO | 5,3'-diallyl-biphenyl-2,4'-diol | HONOKIOL
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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