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Target
Alpha-2A adrenergic receptor
Ligand
BDBM50597777
Substrate
n/a
Meas. Tech.
ChEMBL_2224409 (CHEMBL5137922)
IC50
7054±n/a nM
Citation
 Sheng, K; Song, Y; Lei, F; Zhao, W; Fan, L; Wu, L; Liu, Y; Wu, S; Zhang, Y Research progress in pharmacological activities and structure-activity relationships of tetralone scaffolds as pharmacophore and fluorescent skeleton. Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
ADA2A_RAT | Adra2a | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | Alpha-2D adrenergic receptor | CA2-47
Type:
PROTEIN
Mol. Mass.:
50650.57
Organism:
Rat
Description:
ChEMBL_104693
Residue:
465
Sequence:
MFRQEQPLAEGSFAPMGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACSAPPGGADRRPNGLGPERGAGTAGAEAEPLPTQLNGAPGEPAPTRPRDGDALDLEESSSSEHAERPQGPGKPERGPRAKGKTKASQVKPGDSLPRRGPGAAGPGASGSGQGEERAGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPYQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM50597777
Synonyms:
CHEMBL5187030
Type:
Small organic molecule
Emp. Form.:
C19H18O4
Mol. Mass.:
310.35
SMILES:
COc1ccc(\C=C2/CCc3c(O)cccc3C2=O)cc1OC
Structure:
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