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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50179482
Substrate
n/a
Meas. Tech.
ChEMBL_335897 (CHEMBL859282)
Ki
1±n/a nM
Citation
 Dubernet, M; Defoin, A; Tarnus, C Asymmetric synthesis of the L-fuco-nojirimycin, a nanomolar alpha-L-fucosidase inhibitor. Bioorg Med Chem Lett 16:1172-4 (2006) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase 1 | FUCA1 | FUCO_BOVIN
Type:
PROTEIN
Mol. Mass.:
54093.12
Organism:
Bos taurus
Description:
ChEMBL_335897
Residue:
468
Sequence:
MRSWVVGARLLLLLQLVLVLGAVRLPPCTDPRHCTDPPRYTPDWPSLDSRPLPAWFDEAKFGVFVHWGVFSVPAWGSEWFWWHWQGEKLPQYESFMKENYPPDFSYADFGPRFTARFFNPDSWADLFKAAGAKYVVLTTKHHEGYTNWPSPVSWNWNSKDVGPHRDLVGELGTAIRKRNIRYGLYHSLLEWFHPLYLRDKKNGFKTQYFVNAKTMPELYDLVNRYKPDLIWSDGEWECPDTYWNSTDFLAWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCKDKFQPETLPDHKWEMCTSIDQRSWGYRRDMEMADITNESTIISELVQTVSLGGNYLLNVGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQSEKNSVWYTSKGLAVYAILLHWPEYGILSLISPIATSTTKVTMLGIQKDLKWSLNPSGKGLLVFLPQLPPAALPTEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50179482
Synonyms:
(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidine-2-sulfonic acid | CHEMBL383067
Type:
Small organic molecule
Emp. Form.:
C6H13NO6S
Mol. Mass.:
227.236
SMILES:
C[C@@H]1N[C@@H]([C@@H](O)[C@H](O)[C@@H]1O)S(O)(=O)=O
Structure:
Search PDB for entries with ligand similarity: