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Target
Potassium voltage-gated channel subfamily A member 1
Ligand
BDBM50182587
Substrate
n/a
Meas. Tech.
ChEMBL_334897 (CHEMBL861275)
EC50
1700±n/a nM
Citation
 Harvey, AJ; Baell, JB; Toovey, N; Homerick, D; Wulff, H A new class of blockers of the voltage-gated potassium channel Kv1.3 via modification of the 4- or 7-position of khellinone. J Med Chem 49:1433-41 (2006) [PubMed]  Article 
Target
Name:
Potassium voltage-gated channel subfamily A member 1
Synonyms:
Potassium voltage-gated channel subfamily A member 1 | Voltage-gated potassium channel subunit Kv1.1 | Potassium (voltage dependent) | KCNA1_HUMAN | KCNA1 | Voltage-gated potassium channel subfamily A member 1/beta-1 | Voltage-gated potassium channel
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56451.30
Organism:
Human
Description:
Potassium (voltage dependent) 0 0::Q09470
Residue:
495
Sequence:
MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTTANQNCVNKSKLLTDV
  
Inhibitor
Name:
BDBM50182587
Synonyms:
5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methoxybenzofuran | CHEMBL382154
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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