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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50186735
Substrate
n/a
Meas. Tech.
ChEMBL_353426 (CHEMBL861360)
pH
6.8000±n/a
Ki
>1000000±n/a nM
Comments
extracted
Citation
 Wang, RW; Qiu, XL; Bols, M; Ortega-Caballero, F; Qing, FL Synthesis and biological evaluation of glycosidase inhibitors: gem-difluoromethylenated nojirimycin analogues. J Med Chem 49:2989-97 (2006) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
FUCO_BOVIN | FUCA1 | Alpha-L-fucosidase 1
Type:
PROTEIN
Mol. Mass.:
54093.12
Organism:
Bovine
Description:
ChEMBL_335897
Residue:
468
Sequence:
MRSWVVGARLLLLLQLVLVLGAVRLPPCTDPRHCTDPPRYTPDWPSLDSRPLPAWFDEAKFGVFVHWGVFSVPAWGSEWFWWHWQGEKLPQYESFMKENYPPDFSYADFGPRFTARFFNPDSWADLFKAAGAKYVVLTTKHHEGYTNWPSPVSWNWNSKDVGPHRDLVGELGTAIRKRNIRYGLYHSLLEWFHPLYLRDKKNGFKTQYFVNAKTMPELYDLVNRYKPDLIWSDGEWECPDTYWNSTDFLAWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCKDKFQPETLPDHKWEMCTSIDQRSWGYRRDMEMADITNESTIISELVQTVSLGGNYLLNVGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQSEKNSVWYTSKGLAVYAILLHWPEYGILSLISPIATSTTKVTMLGIQKDLKWSLNPSGKGLLVFLPQLPPAALPTEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50186735
Synonyms:
D-1,4-dideoxy-4,4-difluoromannonojirimycin | CHEMBL208021
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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