Reaction Details Report a problem with these data
Target
Caspase-3
Ligand
BDBM509991
Substrate
n/a
Meas. Tech.
ChEMBL_2294286
IC50
>20000±n/a nM
Citation
 Chen, R; Gao, Y; Liu, H; Li, H; Chen, W; Ma, J Advances in research on 3C-like protease (3CL RSC Med Chem 14:9-21 (2023) [PubMed] 
Target
Name:
Caspase-3
Synonyms:
CPP-32 | Caspase 3 | Caspase-3 subunit p12 | Caspase-3 subunit p17 | Cysteine protease CPP32 | Apopain | CASP-3 | SCA-1 | SREBP cleavage activity 1 | Yama protein | caspase-3 preproprotein | CASP3_HUMAN | CASP3 | CPP32
Type:
Hydrolase; heterotetramer of two heterodimers
Mol. Mass.:
31607.55
Organism:
Human
Description:
n/a
Residue:
277
Sequence:
MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
  
Inhibitor
Name:
BDBM509991
Synonyms:
Jun9-62-2R
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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