Reaction Details Report a problem with these data
Target
O-phosphoserine sulfhydrylase
Ligand
BDBM50550146
Substrate
n/a
Meas. Tech.
ChEMBL_2302130
IC50
480±n/a nM
Citation
 Brunner, K; Steiner, EM; Reshma, RS; Sriram, D; Schnell, R; Schneider, G Profiling of in vitro activities of urea-based inhibitors against cysteine synthases from Mycobacterium tuberculosis. Bioorg Med Chem Lett 27:4582-4587 (2017) [PubMed] 
Target
Name:
O-phosphoserine sulfhydrylase
Synonyms:
2.5.1.113 | CSase B | cysM | CysO-thiocarboxylate-dependent cysteine synthase | Cysteine synthase B | O-phosphoserine sulfhydrylase | O-phosphoserine-specific cysteine synthase | OPS sulfhydrylase | [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
Type:
PROTEIN
Mol. Mass.:
34430.52
Organism:
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:
ChEMBL_120962
Residue:
323
Sequence:
MTRYDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAEADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVADAGWKYLSTGAYAGSLDDAETALEGQLWA
  
Inhibitor
Name:
BDBM50550146
Synonyms:
CHEMBL4757665
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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