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Target
Transcription factor 4
Ligand
BDBM50094484
Substrate
n/a
Meas. Tech.
ChEMBL_2322130
IC50
8700±n/a nM
Citation
 Yang, P; Zhu, Y; Zheng, Q; Meng, S; Wu, Y; Shuai, W; Sun, Q; Wang, G Recent advances of β-catenin small molecule inhibitors for cancer therapy: Current development and future perspectives. Eur J Med Chem 243:0 (2022) [PubMed] 
Target
Name:
Transcription factor 4
Synonyms:
Class B basic helix-loop-helix protein 19 | ITF-2 | Immunoglobulin transcription factor 2 | SEF-2 | SL3-3 enhancer factor 2 | TCF-4 | Transcription factor 4 | ITF2_HUMAN | TCF4 | BHLHB19 | ITF2 | SEF2
Type:
PROTEIN
Mol. Mass.:
71315.43
Organism:
Human
Description:
ChEMBL_117085
Residue:
667
Sequence:
MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM
  
Inhibitor
Name:
BDBM50094484
Synonyms:
CHEMBL2323033 | CHEBI:3556 | US9284299, CGP049090 | US9738628, Compound CGP049090
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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