Reaction Details Report a problem with these data
Target
Adrenocorticotropic hormone receptor
Ligand
BDBM50623111
Substrate
n/a
Meas. Tech.
ChEMBL_2336250
Ki
3.0±n/a nM
Citation
 Kim, SH; Han, S; Zhao, J; Wang, S; Kusnetzow, AK; Reinhart, G; Fowler, MA; Markison, S; Johns, M; Luo, R; Struthers, RS; Zhu, Y; Betz, SF Discovery of CRN04894: A Novel Potent Selective MC2R Antagonist. ACS Med Chem Lett 15:478-485 (2024) [PubMed] 
Target
Name:
Adrenocorticotropic hormone receptor
Synonyms:
ACTH receptor | ACTH-R | Adrenocorticotropic hormone receptor | Adrenocorticotropin receptor | MC2-R | ACTHR_HUMAN | MC2R | ACTHR | Melanocortin receptor 2
Type:
PROTEIN
Mol. Mass.:
33938.44
Organism:
Human
Description:
ChEMBL_306831
Residue:
297
Sequence:
MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW
  
Inhibitor
Name:
BDBM50623111
Synonyms:
CHEMBL5403170
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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