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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50623115
Substrate
n/a
Meas. Tech.
ChEMBL_2336259
IC50
>10000±n/a nM
Citation
 Kim, SH; Han, S; Zhao, J; Wang, S; Kusnetzow, AK; Reinhart, G; Fowler, MA; Markison, S; Johns, M; Luo, R; Struthers, RS; Zhu, Y; Betz, SF Discovery of CRN04894: A Novel Potent Selective MC2R Antagonist. ACS Med Chem Lett 15:478-485 (2024) [PubMed] 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MSH-R | Melanocortin MC1 | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R) | MSHR_HUMAN | MC1R | MSHR | Melanocortin receptor (M1 and M4)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Human
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM50623115
Synonyms:
CHEMBL5414447
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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