Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM50623115
Substrate
n/a
Meas. Tech.
ChEMBL_2336261
IC50
>10000±n/a nM
Citation
 Kim, SH; Han, S; Zhao, J; Wang, S; Kusnetzow, AK; Reinhart, G; Fowler, MA; Markison, S; Johns, M; Luo, R; Struthers, RS; Zhu, Y; Betz, SF Discovery of CRN04894: A Novel Potent Selective MC2R Antagonist. ACS Med Chem Lett 15:478-485 (2024) [PubMed] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) | MC4R_HUMAN | MC4R
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Human
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM50623115
Synonyms:
CHEMBL5414447
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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