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Target
Angiotensin-converting enzyme 2
Ligand
BDBM50624133
Substrate
n/a
Meas. Tech.
ChEMBL_2340226
Kd
29±n/a nM
Citation
 Harman, MAJ; Stanway, SJ; Scott, H; Demydchuk, Y; Bezerra, GA; Pellegrino, S; Chen, L; Brear, P; Lulla, A; Hyvönen, M; Beswick, PJ; Skynner, MJ Structure-Guided Chemical Optimization of Bicyclic Peptide ( J Med Chem 66:9881-9893 (2023) [PubMed] 
Target
Name:
Angiotensin-converting enzyme 2
Synonyms:
Angiotensin-converting enzyme-related carboxypeptidase | ACEH | ACE-related carboxypeptidase | Angiotensin-converting enzyme homolog | Metalloprotease MPROT15 | ACE2_HUMAN | ACE2
Type:
Enzyme
Mol. Mass.:
92448.86
Organism:
Human
Description:
n/a
Residue:
805
Sequence:
MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNPGFQNTDDVQTSF
  
Inhibitor
Name:
BDBM50624133
Synonyms:
CHEMBL5415513
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: