Reaction Details Report a problem with these data
Target
4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic
Ligand
BDBM50625572
Substrate
n/a
Meas. Tech.
ChEMBL_2346406
IC50
66200±n/a nM
Citation
 Christoff, RM; Al Bayer, M; Soares da Costa, TP; Perugini, MA; Abbott, BM Enhancing allosteric inhibition of dihydrodipicolinate synthase through the design and synthesis of novel dimeric compounds. RSC Med Chem 14:1698-1703 (2023) [PubMed] 
Target
Name:
4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic
Synonyms:
4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic | 4.3.3.7 | DHDPS | DHDPS1 | DHPS1 | HTPA synthase 1
Type:
PROTEIN
Mol. Mass.:
40624.00
Organism:
Arabidopsis thaliana
Description:
ChEMBL_121379
Residue:
365
Sequence:
MSALKNYGLISIDSALHFPRSNQLQSYKRRNAKWVSPIAAVVPNFHLPMRSLEDKNRTNTDDIRSLRVITAIKTPYLPDGRFDLQAYDDLVNTQIENGAEGVIVGGTTGEGQLMSWDEHIMLIGHTVNCFGGRIKVIGNTGSNSTREAIHATEQGFAMGMHGALHINPYYGKTSIEGMNAHFQTVLHMGPTIIYNVPGRTCQDIPPQVIFKLSQNPNMAGVKECVGNNRVEEYTEKGIVVWSGNDDQCHDSRWDHGATGVISVTSNLVPGLMRKLMFEGRNSALNAKLLPLMDWLFQEPNPIGVNTALAQLGVARPVFRLPYVPLPLSKRIEFVKLVKEIGREHFVGDRDVQVLDDDDFILIGRY
  
Inhibitor
Name:
BDBM50625572
Synonyms:
CHEMBL2263549
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: