Reaction Details
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4-hydroxy-tetrahydrodipicolinate synthase 2, chloroplastic
Ligand
BDBM50625573
Substrate
n/a
Meas. Tech.
ChEMBL_2346407
IC50
33900±n/a nM
Citation
Christoff, RM; Al Bayer, M; Soares da Costa, TP; Perugini, MA; Abbott, BM Enhancing allosteric inhibition of dihydrodipicolinate synthase through the design and synthesis of novel dimeric compounds. RSC Med Chem 14:1698-1703 (2023) [PubMed] More Info.:
Target
Name:
4-hydroxy-tetrahydrodipicolinate synthase 2, chloroplastic
Synonyms:
4-hydroxy-tetrahydrodipicolinate synthase 2, chloroplastic | 4.3.3.7 | DHDPS2 | HTPA synthase 2
Type:
PROTEIN
Mol. Mass.:
40297.32
Organism:
Arabidopsis thaliana
Description:
ChEMBL_121374
Residue:
365
Sequence:
MAALKGYGLCSMDSALQFPCPKLFNSYKRRSSKWVSPKAAVVPNFHLPMRSLEVKNRTNTDDIKALRVITAIKTPYLPDGRFDLEAYDDLVNIQIQNGAEGVIVGGTTGEGQLMSWDEHIMLIGHTVNCFGGSIKVIGNTGSNSTREAIHATEQGFAVGMHAALHINPYYGKTSIEGLIAHFQSVLHMGPTIIYNVPGRTGQDIPPRAIFKLSQNPNLAGVKECVGNKRVEEYTENGVVVWSGNDDECHDSRWDYGATGVISVTSNLVPGLMRKLMFEGRNSSLNSKLLPLMAWLFHEPNPIGINTALAQLGVSRPVFRLPYVPLPLSKRLEFVKLVKEIGREHFVGEKDVQALDDDDFILIGRY
Inhibitor
Name:
BDBM50625573
Synonyms:
CHEMBL5437863
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
