Reaction Details Report a problem with these data
Target
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Ligand
BDBM50626102
Substrate
n/a
Meas. Tech.
ChEMBL_2349155
IC50
<100±n/a nM
Citation
 Sabnis, RW Emopamil-Binding Protein Inhibitors for Treating Multiple Sclerosis. ACS Med Chem Lett 15:163-164 (2024) [PubMed] 
Target
Name:
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Synonyms:
Cholestenol Delta-isomerase | D8-D7 sterol isomerase | Delta(8)-Delta(7) sterol isomerase | Emopamil-binding protein | 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | EBP_HUMAN | EBP | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/Delta(24)-sterol reductase | Anti-estrogen binding site (AEBS)
Type:
PROTEIN
Mol. Mass.:
26358.51
Organism:
Human
Description:
ChEMBL_873432
Residue:
230
Sequence:
MTTNAGPLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGTWRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVCMETITACLWGPLSLWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELGHPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTHAQSTLDAKATKAKSKKN
  
Inhibitor
Name:
BDBM50626102
Synonyms:
CHEMBL5409418
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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