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Target
Small conductance calcium-activated potassium channel protein 3
Ligand
BDBM50478473
Substrate
n/a
Meas. Tech.
ChEMBL_2349182
Ki
461±n/a nM
Citation
 Vitello, R; Taouba, H; Derand, M; Liégeois, JF The Bis(1,2,3,4-tetrahydroisoquinoline) Alkaloids Cepharanthine and Berbamine Are Ligands of SK Channels. ACS Med Chem Lett 15:215-220 (2024) [PubMed] 
Target
Name:
Small conductance calcium-activated potassium channel protein 3
Synonyms:
Small conductance calcium-activated potassium channel protein 3 (KCa2.3) | Small conductance calcium-activated potassium channel protein 3 | KCNN3_HUMAN | KCNN3 | K3
Type:
Protein
Mol. Mass.:
82053.75
Organism:
Human
Description:
Q9UGI6
Residue:
731
Sequence:
MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQHAGTTASSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSSSSC
  
Inhibitor
Name:
BDBM50478473
Synonyms:
CHEBI:49 | NSC-77037 | FANCHININ | Tetrandrine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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