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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50383373
Substrate
n/a
Meas. Tech.
ChEMBL_2372367
EC50
3620±n/a nM
Citation
 Hyun, YE; An, S; Kim, M; Park, IG; Yoon, S; Javaid, HMA; Vu, TNL; Kim, G; Choi, H; Lee, HW; Noh, M; Huh, JY; Choi, S; Kim, HR; Jeong, LS Structure-Activity Relationships of Truncated 1'-Homologated Carbaadenosine Derivatives as New PPARγ/δ Ligands: A Study on Sugar Puckering Affecting Binding to PPARs. J Med Chem 66:4961-4978 (2023) [PubMed] 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
Peroxisome proliferator-activated receptor delta | PPAR delta | NUCI | Nuclear hormone receptor 1 | NUC1 | Nuclear receptor subfamily 1 group C member 2 | Peroxisome proliferator-activated receptor beta | PPAR-beta | PPARD_HUMAN | PPARD | NR1C2 | PPARB | Peroxisome proliferator-activated receptor
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Human
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50383373
Synonyms:
GSK0660 | CHEMBL592652
Type:
Small organic molecule
Emp. Form.:
C19H18N2O5S2
Mol. Mass.:
n/a
SMILES:
COC(=O)c1sccc1S(=O)(=O)Nc1ccc(Nc2ccccc2)cc1OC
Structure:
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