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Target
Arginase-1
Ligand
BDBM50642489
Substrate
n/a
Meas. Tech.
ChEMBL_2457414
IC50
280±n/a nM
Citation
 Gzik, A; Borek, B; Chrzanowski, J; Jedrzejczak, K; Dziegielewski, M; Brzezinska, J; Nowicka, J; Grzybowski, MM; Rejczak, T; Niedzialek, D; Wieczorek, G; Olczak, J; Golebiowski, A; Zaslona, Z; Blaszczyk, R Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion. Eur J Med Chem 264:0[PubMed] 
Target
Name:
Arginase-1
Synonyms:
Liver-type arginase | Type I arginase | ARGI1_HUMAN | ARG1
Type:
PROTEIN
Mol. Mass.:
34737.53
Organism:
Human
Description:
ChEMBL_978893
Residue:
322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK
  
Inhibitor
Name:
BDBM50642489
Synonyms:
CHEMBL5569123
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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