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Target
Excitatory amino acid transporter 3
Ligand
BDBM50644326
Substrate
n/a
Meas. Tech.
ChEMBL_2465785
EC50
0.200000±n/a nM
Citation
 Fontana, ACK; Poli, ANR; Gour, J; Srikanth, YVV; Anastasi, N; Ashok, D; Khatiwada, A; Reeb, KL; Cheng, MH; Bahar, I; Rawls, SM; Salvino, JM Synthesis and Structure-Activity Relationships for Glutamate Transporter Allosteric Modulators. J Med Chem 67:6119-6143[PubMed] 
Target
Name:
Excitatory amino acid transporter 3
Synonyms:
Excitatory Amino Acid EAAT3 | EAA3_HUMAN | SLC1A1 | EAAC1 | EAAT3 | HEAAC1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57096.71
Organism:
Human
Description:
Excitatory Amino Acid EAAT3 0 HUMAN::P43005
Residue:
524
Sequence:
MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFALESTILDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
  
Inhibitor
Name:
BDBM50644326
Synonyms:
CHEMBL5593916
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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